diff --git a/waflib/Tools/c_config.py b/waflib/Tools/c_config.py
index 98187fac..03b6bf61 100644
--- a/waflib/Tools/c_config.py
+++ b/waflib/Tools/c_config.py
@@ -68,6 +68,7 @@ MACRO_TO_DEST_CPU = {
 '__s390__'    : 's390',
 '__sh__'      : 'sh',
 '__xtensa__'  : 'xtensa',
+'__e2k__'     : 'e2k',
 }
 
 @conf