diff --git a/gcc/init-regs.c b/gcc/init-regs.c
index 903c6541f10..72e898f3e33 100644
--- a/gcc/init-regs.c
+++ b/gcc/init-regs.c
@@ -105,7 +105,10 @@ initialize_uninitialized_regs (void)
 
 		  start_sequence ();
 		  emit_clobber (reg);
-		  emit_move_insn (reg, CONST0_RTX (GET_MODE (reg)));
+		  /* PR98872: Only emit an initialization if MODE has a
+		     CONST0_RTX defined.  */
+		  if (CONST0_RTX (GET_MODE (reg)))
+		    emit_move_insn (reg, CONST0_RTX (GET_MODE (reg)));
 		  move_insn = get_insns ();
 		  end_sequence ();
 		  emit_insn_before (move_insn, insn);
diff --git a/gcc/testsuite/gcc.target/powerpc/pr98872.c b/gcc/testsuite/gcc.target/powerpc/pr98872.c
new file mode 100644
index 00000000000..f33ad9b48b6
--- /dev/null
+++ b/gcc/testsuite/gcc.target/powerpc/pr98872.c
@@ -0,0 +1,19 @@
+/* PR target/98872 */
+/* { dg-require-effective-target power10_ok } */
+/* { dg-options "-O2 -mdejagnu-cpu=power10" } */
+
+/* Verify we do not ICE on the following tests.  */
+
+void
+foo (__vector_quad *dst)
+{
+  __vector_quad acc;
+  *dst = acc;
+}
+
+void
+bar (__vector_pair *dst)
+{
+  __vector_pair pair;
+  *dst = pair;
+}