diff --git a/libstdc++-v3/include/bits/deque.tcc b/libstdc++-v3/include/bits/deque.tcc
index 80f1813bc76..03e0a505e14 100644
--- a/libstdc++-v3/include/bits/deque.tcc
+++ b/libstdc++-v3/include/bits/deque.tcc
@@ -454,6 +454,9 @@ _GLIBCXX_BEGIN_NAMESPACE_CONTAINER
 		 __cur_node < this->_M_impl._M_finish._M_node;
 		 ++__cur_node)
 	      {
+		if (__n < _S_buffer_size())
+		  __builtin_unreachable(); // See PR 100516
+
 		_ForwardIterator __mid = __first;
 		std::advance(__mid, _S_buffer_size());
 		std::__uninitialized_copy_a(__first, __mid, *__cur_node,
diff --git a/libstdc++-v3/testsuite/23_containers/deque/100516.cc b/libstdc++-v3/testsuite/23_containers/deque/100516.cc
new file mode 100644
index 00000000000..ef32ae10545
--- /dev/null
+++ b/libstdc++-v3/testsuite/23_containers/deque/100516.cc
@@ -0,0 +1,14 @@
+// { dg-options "-O2 -Wstringop-overread" }
+// { dg-do compile { target c++11 } }
+
+// Bug 100516
+// Unexpected -Wstringop-overread in deque<char> initialization from empty
+// initializer_list
+
+#include <deque>
+
+void f()
+{
+    std::initializer_list<char> il{};
+    std::deque<char>{il};
+}