diff --git a/gcc/symtab.c b/gcc/symtab.c
index 8c4cb70b015..c7ea8ecef74 100644
--- a/gcc/symtab.c
+++ b/gcc/symtab.c
@@ -1959,6 +1959,8 @@ symtab_node::noninterposable_alias (void)
   /* If aliases aren't supported by the assembler, fail.  */
   if (!TARGET_SUPPORTS_ALIASES)
     return NULL;
+  else if (lookup_attribute ("target_clones", DECL_ATTRIBUTES (node->decl)))
+    return NULL;
 
   /* Otherwise create a new one.  */
   new_decl = copy_node (node->decl);
diff --git a/gcc/testsuite/gcc.target/i386/pr101261.c b/gcc/testsuite/gcc.target/i386/pr101261.c
new file mode 100644
index 00000000000..d25d1a202c2
--- /dev/null
+++ b/gcc/testsuite/gcc.target/i386/pr101261.c
@@ -0,0 +1,11 @@
+/* PR middle-end/101261 */
+/* { dg-do compile { target fpic } } */
+/* { dg-options "-fno-semantic-interposition -fPIC" } */
+/* { dg-require-ifunc "" } */
+
+void
+__attribute__((target_clones("default", "avx2")))
+dt_ioppr_transform_image_colorspace()
+{
+  dt_ioppr_transform_image_colorspace();
+}