diff --git a/block/qcow2.c b/block/qcow2.c
index ee040a49cd..4ac1a45e61 100644
--- a/block/qcow2.c
+++ b/block/qcow2.c
@@ -1118,8 +1118,9 @@ static int qcow2_update_options(BlockDriverState *bs, QDict *options,
     return ret;
 }
 
-static int qcow2_do_open(BlockDriverState *bs, QDict *options, int flags,
-                         Error **errp)
+/* Called with s->lock held.  */
+static int coroutine_fn qcow2_do_open(BlockDriverState *bs, QDict *options,
+                                      int flags, Error **errp)
 {
     BDRVQcow2State *s = bs->opaque;
     unsigned int len, i;
@@ -1498,8 +1499,6 @@ static int qcow2_do_open(BlockDriverState *bs, QDict *options, int flags,
         }
     }
 
-    /* Initialise locks */
-    qemu_co_mutex_init(&s->lock);
     bs->supported_zero_flags = header.version >= 3 ? BDRV_REQ_MAY_UNMAP : 0;
 
     /* Repair image if dirty */
@@ -1545,16 +1544,53 @@ static int qcow2_do_open(BlockDriverState *bs, QDict *options, int flags,
     return ret;
 }
 
+typedef struct QCow2OpenCo {
+    BlockDriverState *bs;
+    QDict *options;
+    int flags;
+    Error **errp;
+    int ret;
+} QCow2OpenCo;
+
+static void coroutine_fn qcow2_open_entry(void *opaque)
+{
+    QCow2OpenCo *qoc = opaque;
+    BDRVQcow2State *s = qoc->bs->opaque;
+
+    qemu_co_mutex_lock(&s->lock);
+    qoc->ret = qcow2_do_open(qoc->bs, qoc->options, qoc->flags, qoc->errp);
+    qemu_co_mutex_unlock(&s->lock);
+}
+
 static int qcow2_open(BlockDriverState *bs, QDict *options, int flags,
                       Error **errp)
 {
+    BDRVQcow2State *s = bs->opaque;
+    QCow2OpenCo qoc = {
+        .bs = bs,
+        .options = options,
+        .flags = flags,
+        .errp = errp,
+        .ret = -EINPROGRESS
+    };
+
     bs->file = bdrv_open_child(NULL, options, "file", bs, &child_file,
                                false, errp);
     if (!bs->file) {
         return -EINVAL;
     }
 
-    return qcow2_do_open(bs, options, flags, errp);
+    /* Initialise locks */
+    qemu_co_mutex_init(&s->lock);
+
+    if (qemu_in_coroutine()) {
+        /* From bdrv_co_create.  */
+        qcow2_open_entry(&qoc);
+    } else {
+        qemu_coroutine_enter(qemu_coroutine_create(qcow2_open_entry, &qoc));
+        BDRV_POLL_WHILE(bs, qoc.ret == -EINPROGRESS);
+    }
+    return qoc.ret;
 }
 
 static void qcow2_refresh_limits(BlockDriverState *bs, Error **errp)