diff --git a/hw/virtio/virtio-iommu.c b/hw/virtio/virtio-iommu.c
index 7dd15c5eac..7b64892351 100644
--- a/hw/virtio/virtio-iommu.c
+++ b/hw/virtio/virtio-iommu.c
@@ -170,11 +170,39 @@ static void virtio_iommu_notify_unmap(IOMMUMemoryRegion *mr, hwaddr virt_start,
     memory_region_notify_iommu(mr, 0, entry);
 }
 
+static gboolean virtio_iommu_notify_unmap_cb(gpointer key, gpointer value,
+                                             gpointer data)
+{
+    VirtIOIOMMUInterval *interval = (VirtIOIOMMUInterval *) key;
+    IOMMUMemoryRegion *mr = (IOMMUMemoryRegion *) data;
+
+    virtio_iommu_notify_unmap(mr, interval->low, interval->high);
+
+    return false;
+}
+
+static gboolean virtio_iommu_notify_map_cb(gpointer key, gpointer value,
+                                           gpointer data)
+{
+    VirtIOIOMMUMapping *mapping = (VirtIOIOMMUMapping *) value;
+    VirtIOIOMMUInterval *interval = (VirtIOIOMMUInterval *) key;
+    IOMMUMemoryRegion *mr = (IOMMUMemoryRegion *) data;
+
+    virtio_iommu_notify_map(mr, interval->low, interval->high,
+                            mapping->phys_addr, mapping->flags);
+
+    return false;
+}
+
 static void virtio_iommu_detach_endpoint_from_domain(VirtIOIOMMUEndpoint *ep)
 {
+    VirtIOIOMMUDomain *domain = ep->domain;
+
     if (!ep->domain) {
         return;
     }
+    g_tree_foreach(domain->mappings, virtio_iommu_notify_unmap_cb,
+                   ep->iommu_mr);
     QLIST_REMOVE(ep, next);
     ep->domain = NULL;
 }
@@ -317,6 +345,10 @@ static int virtio_iommu_attach(VirtIOIOMMU *s,
 
     ep->domain = domain;
 
+    /* Replay domain mappings on the associated memory region */
+    g_tree_foreach(domain->mappings, virtio_iommu_notify_map_cb,
+                   ep->iommu_mr);
+
     return VIRTIO_IOMMU_S_OK;
 }