diff --git a/target/s390x/helper.h b/target/s390x/helper.h
index 054ccd686d..69249a5249 100644
--- a/target/s390x/helper.h
+++ b/target/s390x/helper.h
@@ -104,6 +104,7 @@ DEF_HELPER_FLAGS_1(popcnt, TCG_CALL_NO_RWG_SE, i64, i64)
 DEF_HELPER_FLAGS_1(stfl, TCG_CALL_NO_RWG, void, env)
 DEF_HELPER_2(stfle, i32, env, i64)
 DEF_HELPER_FLAGS_2(lpq, TCG_CALL_NO_WG, i64, env, i64)
+DEF_HELPER_FLAGS_4(stpq, TCG_CALL_NO_WG, void, env, i64, i64, i64)
 
 #ifndef CONFIG_USER_ONLY
 DEF_HELPER_3(servc, i32, env, i64, i64)
diff --git a/target/s390x/insn-data.def b/target/s390x/insn-data.def
index 32dee40269..73dd05daf0 100644
--- a/target/s390x/insn-data.def
+++ b/target/s390x/insn-data.def
@@ -796,6 +796,8 @@
 /* STORE ACCESS MULTIPLE */
     C(0x9b00, STAM,    RS_a,  Z,   0, a2, 0, 0, stam, 0)
     C(0xeb9b, STAMY,   RSY_a, LD,  0, a2, 0, 0, stam, 0)
+/* STORE PAIR TO QUADWORD */
+    C(0xe38e, STPQ,    RXY_a, Z,   0, a2, r1_P, 0, stpq, 0)
 
 /* SUBTRACT */
     C(0x1b00, SR,      RR_a,  Z,   r1, r2, new, r1_32, sub, subs32)
diff --git a/target/s390x/mem_helper.c b/target/s390x/mem_helper.c
index f48908cecb..a8988e0293 100644
--- a/target/s390x/mem_helper.c
+++ b/target/s390x/mem_helper.c
@@ -1692,6 +1692,30 @@ uint64_t HELPER(lpq)(CPUS390XState *env, uint64_t addr)
     return hi;
 }
 
+/* store pair to quadword */
+void HELPER(stpq)(CPUS390XState *env, uint64_t addr,
+                  uint64_t low, uint64_t high)
+{
+    uintptr_t ra = GETPC();
+
+    if (parallel_cpus) {
+#ifndef CONFIG_ATOMIC128
+        cpu_loop_exit_atomic(ENV_GET_CPU(env), ra);
+#else
+        int mem_idx = cpu_mmu_index(env, false);
+        TCGMemOpIdx oi = make_memop_idx(MO_TEQ | MO_ALIGN_16, mem_idx);
+
+        Int128 v = int128_make128(low, high);
+        helper_atomic_sto_be_mmu(env, addr, v, oi, ra);
+#endif
+    } else {
+        check_alignment(env, addr, 16, ra);
+
+        cpu_stq_data_ra(env, addr + 0, high, ra);
+        cpu_stq_data_ra(env, addr + 8, low, ra);
+    }
+}
+
 /* Execute instruction.  This instruction executes an insn modified with
    the contents of r1.  It does not change the executed instruction in memory;
    it does not change the program counter.
diff --git a/target/s390x/translate.c b/target/s390x/translate.c
index 10019edd53..95f91d4f08 100644
--- a/target/s390x/translate.c
+++ b/target/s390x/translate.c
@@ -4203,6 +4203,12 @@ static ExitStatus op_stmh(DisasContext *s, DisasOps *o)
     return NO_EXIT;
 }
 
+static ExitStatus op_stpq(DisasContext *s, DisasOps *o)
+{
+    gen_helper_stpq(cpu_env, o->in2, o->out2, o->out);
+    return NO_EXIT;
+}
+
 static ExitStatus op_srst(DisasContext *s, DisasOps *o)
 {
     gen_helper_srst(o->in1, cpu_env, regs[0], o->in1, o->in2);