diff --git a/block/qcow2.c b/block/qcow2.c
index e8cbcc1ec1..b524b0c53f 100644
--- a/block/qcow2.c
+++ b/block/qcow2.c
@@ -4355,6 +4355,11 @@ qcow2_co_pwritev_compressed_part(BlockDriverState *bs,
         return -EINVAL;
     }
 
+    if (offset_into_cluster(s, bytes) &&
+        (offset + bytes) != (bs->total_sectors << BDRV_SECTOR_BITS)) {
+        return -EINVAL;
+    }
+
     while (bytes && aio_task_pool_status(aio) == 0) {
         uint64_t chunk_size = MIN(bytes, s->cluster_size);